Meleady, L.*, Towriss, M.*,  Kim, J., Bacarac, V., Dang, V., Rowland, M., Ciernia, A.V. (2023). Histone deacetylase 3 regulates microglial function through histone deacetylation. Epigenetics. 18(1).

*co-first authors

Towriss, M., MacVicar, B., and Ciernia AV. (2023) Modelling Microglial Innate Immune Memory In Vitro: Understanding the role of cellular metabolic flux in innate immune memory. International Journal of Molecular Sciences. 24(10), 8967.

Sullivan O, Ciernia AV. (2022). Work hard, play hard: how sexually differentiated microglia work to shape social play and reproductive behavior. Front Behav Neurosci. 12;16:989011. 

Rowland, M. E., Jajarmi, J. M., Osborne, T., & Ciernia, A. V. (2022). Insights Into the Emerging Role of Baf53b in Autism Spectrum DisorderFrontiers in molecular neuroscience15, 805158. 

Hughes, H.K., Rowland, M.E., Onore, C.E., Ciernia, A.V. & Ashwood, P.A. Dysregulated gene expression associated with inflammatory and translation pathways in activated monocytes from children with autism spectrum disorderTransl Psychiatry 12, 39 (2022).

Jao J., Ciernia A.V. (2021). MGEnrichment: A web application for microglia gene list enrichment analysis. PLoS Comput Biol 17(11): e1009160.

Data Availability: All relevant data are within the manuscript and its Supporting Information files. Relevant code can be found here:

Kim, J. & A.V. Ciernia. (2020). Chromatin dynamics and genetic variation combine to regulate innate immune memory. Journal of Clinical & Cellular Immunology. 11(4):1-5.

Ciernia, A.V., Link, V.M., Careaga, M., Lasalle, J.M., & Ashwood, P. (2020). Genetic variants drive epigenetic regulation of endotoxin tolerance in BTBR macrophages. Brain, Behavior and Immunity. S0889-1591(20)30260-9.

Kim, H.K., Gschwind, T., Nguyen, T.M., Bui, A.D., Felong, S., Ampig, K., Suh, D., Ciernia, A.V., Wood, M.A., & Soltesz, I. 2020). Optogenetic intervention of seizures improves spatial memory in a mouse model of chronic temporal lobe epilepsy, Epilepsia. 61: 561– 571.

Vogel Ciernia, A., Laufer, B.I., Hwang, H., Dunaway, K.W., Mordaunt, C.E., Coulson, R.L., A., Yasui, D.H., & LaSalle, J.M. (2019). Epigenomic convergence of neural-immune risk factors in neurodevelopmental disorder cortex. Cerebral Cortex. 30(2):640-655

Laufer, B.I., Hwang, H., Vogel Ciernia, A., Mordaunt, C.E., & LaSalle, J.M. (2019). Whole genome bisulfite sequencing of Down syndrome brain reveals regional DNA hypermethylation and novel disorder insights, Human Molecular Genetics, 14(7), 672-684.

Vogel Ciernia, A., Yasui, D.H, Pride, M.C., Durbin-Johnson, B., Noronha, A., Chang, A., Knotts, T.A., Rutkowsky, J., Ramsey, J.J., Crawley, J.N., & LaSalle, J.M. (2018). MeCP2 isoform e1 mutant mice recapitulate motor and metabolic phenotypes of Rett syndrome, Human Molecular Genetics, 27(3), 4077-4093.

Kwapis, J.L., Alaghband Y., Kramár, E.A., Vogel Ciernia, A., López, A.J., White, A.O., Shu, G., Rhee D, Michael CM, Montellier E., Liu Y, Magnan CN, Sassone-Corsi P, Baldi P, Matheos DP, Wood, M.A. (2018). Epigenetic regulation of the circadian gene Per1 in the hippocampus mediates age-related changes in memory and synaptic plasticity. Nature Communications, 9(1), 3323.

Vogel Ciernia, A., Laufer, B.I., Mordaunt, C.E., Dunaway, K.W., Mordaunt, C.E., Coulson, R.L., Totah, T.S., Stolzenberg, D.S., Frahm, J., Singh-Taylor, A., Baram, T.Z., LaSalle, J.M., & Yasui, D.H. (2018). Experience-dependent neuroplasticity of the developing hypothalamus:  integrative epigenomic approaches. Epigenetics, 3, 1-37.

Coulson, R.L., Yasui, D.H., Dunaway, K.W., Laufer, B.I., Vogel Ciernia, A., Mordaunt, C.E., Totah, T.S., LaSalle, J.M. (2018). Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex. Nature Communications, 9(1):1616.

Vogel Ciernia, A., Careaga, M., LaSalle, J.M., & Ashwood, P. (2018). Microglia from offspring of dams with allergic asthma exhibit epigenomic alterations to genes dysregulated in autism. Glia, 66(3):501-521.

Lopez, S.J., Dunaway, K., Islam, M.S., Mordaunt, C.,Vogel Ciernia, A., Meguro-Horike, M., Horike, S., Segal, D.J., & LaSalle, J.M. (2017). UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons, Epigenetics, 2(11):982-990.

Vogel Ciernia, A., Pride, M., Durbin-Johnson, B., Noronha, A., Chang, A., Yasui, D.H., Crawley, J.N., & LaSalle, J.M. (2017). Early motor phenotype detection in a female mouse model of Rett syndrome is improved by cross-fostering. Human Molecular Genetics, 26(10):1839-1854.

Vogel Ciernia, A. Kramár, E., Matheos, D.P., Havekes, R., Hemstedt, T.J., Magnan, C.N., Sakata, K., Tran, A., Azzawi, S., Lopez, A., Dang, R., Wang, W., Trieu, B., Tong, J., Barrett, R.M., Post, R.J., Baldi, P., Abel, T., Lynch, G. & Wood, M.A. Mutation of neuron-specific chromatin remodeling subunit BAF53b: Rescue of plasticity and memory by manipulating actin remodeling. Learning & Memory, 24(5):199-209.

Dunaway K.W., Islam M.S., Coulson R.L., Lopez S.J., Vogel Ciernia A., Chu R.G., Yasui DH., Pessah I.N., Lott P., Mordaunt C., Meguro-Horike M., Horike S., Korf I., LaSalle J.M. (2016). Cumulative impact of large chromosomal duplications and polychlorinated biphenyl exposure on methylation, chromatin, and expression of autism genes.  Cell Reports, 17(11):3025-3048.

Vogel Ciernia, A. & LaSalle, J. (2016).The landscape of DNA methylation amid a perfect storm of autism aetiologies. Nature Reviews Neuroscience, 17(7): 411-423.

Lopez, A. J., Kramar, E., Matheos, D. P., White, A. O., Kwapis, J., Vogel-Ciernia, A., Sakata, K., Espinoza, M. & Wood. M. A.(2016). Promotor-specific effects of DREADD Modulation on Hippocampal Synaptic Plasticity and Memory Formation. The Journal of Neuroscience, 36(12): 3588-3599.

Vogel-Ciernia, A. & Wood, M.A. (2014). Examining Memory for Object Location and Object Recognition in Mice. Current Protocol, 69(8.31) 8.31.1–8.31.17.

Bharadwaj, R., Peter, C.J., Jiang, Y., Roussos, P., Vogel-Ciernia, A., Shen, E., Mitchell, A., Mao,W.,  Whittle, C., Dincer, A., Jakovcevski, M., Pothula, V., Rasmussen, T.P., Giakoumaki, S.G., Bitsios, P., Gardner, P.D., Ernst, P., Ghose, S., Sklar, P., Haroutunian, V., Tamminga, C., Myers,  R.H., Futai, K., Wood, M.A., & Akbarian, S. (2014). Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition.  Neuron, 84(5): 997-1008.

Vogel-Ciernia, A. & Wood, M.A. (2014). Neuron-specific chromatin remodeling: A missing link in epigenetic mechanisms underlying synaptic plasticity, memory, and intellectual disability disorders. Neuropharmacology, 80:18-27.

Gayzur, N.D, Langley, L.K., Friesen, C.K., Wyman, S.V., Saville, A.L., Ciernia, A.T., Padmanabhan, G. (2014). Reflexive orienting in response to short- and long-duration gaze cues in young, young-old, and old-old adults. Attention, Perception, & Psychophysics, 76(2): 407-419.

Vogel-Ciernia, A. Matheos, D.P., Barrett, R.M., Kramár, E., Azzawi, S., Chen, Y., Magnan, C.N., Zeller, M., Sylvain, A., Haettig, J., Jia, Y., Tran, A., Dang, R., Post, R.J., Chabrier, M., Babayan, A., Wu, J.I., Crabtree, G.R., Baldi, P., Baram, T.Z., Lynch, G. & Wood, M.A. (2013). The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory. Nature Neuroscience, 16(5): 552-561.

Vashishtha, M. Ng, C.W., Yildirim, F., Gipson T., Kratter, I.H., Bodai, L., Song, W., Lau, A., Labadorf, A., Vogel-Ciernia, A., Troncoso, J., Ross, C.A., Bates, G.P., Krainc, D., Sadri-Vakili, G., Finkbeiner, S., Marsh, J.L., Housman, D.E., Fraenkel, E., Thompson, L.M. (2013) Targeting H3K4 Trimethylation in Huntington Disease. PNAS, 110(32): E3027-E3036.

McNulty, S., Barrett, R.M., Vogel-Ciernia, A., Malvaez, M., Hernandez, N., Davatolhagh, M.F., Matheos, D.P., Schiffman, A. & Wood, M.A. (2012). Differential roles for Nr4a1 and Nr4a2 in object location versus object recognition long-term memory. Learning & Memory, 19:588-592.

Vogel-Ciernia, A. & Wood, M.A. (2012). Molecular Brake Pad Hypothesis: Pulling Off the Brakes for Emotional Memory. Reviews in the Neurosciences, 23(5-6): 607-626.

Langley, L.K., Friesen, C.K., Saville, A.L., & Ciernia, A.T. (2011). Timing of Reflexive Visuospatial Orienting in Young, Young-Old, and Old-Old Adults. Attention, Perception, & Psychophysics, 73(5):1546-61.